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Kyowa Self-Affirms GRAS Status for L-Citrulline

Kyowa Hakko U.S.A., Inc., New York, NY, the wholly owned subsidiary of KYOWA HAKKO BIO CO., LTD. (Kyowa), has announced it has completed GRAS (Generally Recognized As Safe) self-affirmation for the valuable amino acid L-Citrulline.
 
L-Citrulline is an amino acid that plays an important role in nitric oxide (NO) metabolism and regulation. L-Citrulline is converted to L-Arginine in the body to support L-Arginine and NO levels. Increased production of NO promotes vascular dilation, which improves oxygen and blood circulation throughout the body. L-Citrulline is also expected to relieve muscle fatigue through ammonia elimination. Antioxidant action and heart protection are also known.
 
“We are extremely proud to announce GRAS for our amino acid L-Citrulline, and look forward to working with manufactures to incorporate it into foods and beverages,” said Dr. Toshikazu Kamiya, President & CEO of Kyowa Hakko USA.

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